CHAMBER was created by researchers at the MRC Brain Network Dynamics Unit to support neuroscience discovery, promote data sharing and reproducibility, and positively impact on the ‘3Rs’ through refining and reducing the use of animals in research.
CHAMBER is a free community resource. It can be readily accessed and used by all stakeholders, under the terms of a CC BY-SA 4.0 licence.
CHAMBER’s images have submicron resolution, are annotated for regions of interest and stereotaxic landmarks, offer a ‘Google Maps-like’ navigation experience, come with detailed experiment metadata, and can be downloaded for further use.
The CHAMBER team members are Kouichi C. Nakamura, Ben Micklem, Giulio Spagnol, Naomi Berry, Andrew Sharott, and Peter J. Magill. The advantages of using chemoarchitectonic data to delineate functionally-specialized brain regions are highlighted by the team’s study of the motor thalamus (see Nakamura et al. 2014). Not so coincidentally, the term thalamus originates from the Greek word thalamos (θάλαμος), which means “[inner] chamber".