This dataset contains the waveforms of dentate spikes extracted from the local field potential (sampled at 1 kHz) of the dorsal hippocampal formation of 8 mice using linear probes. These animals were subjects of research across three different laboratories, and the raw data from these recordings have been previously analyzed in distinct original studies. For comprehensive information, consult the relevant publication linked below.

Each file within this dataset corresponds to the data collected from a single animal and is structured as a 3D matrix of channels by dentate spikes by amplitude samples. Each dentate spike is composed of 401 amplitude samples centred at the peak, with each sample representing a one-millisecond time bin. I.e., being the DS peak at t=0, the time window ranges from −200 to 200 ms. The number of channels varies according to the linear probe used in each mouse. The index of the channel in hilus, which was chosen for the DS detection, is indicated below:

Mouse A   (reference 4) – channel index   8
Mouse B1 (reference 3) – channel index 31
Mouse B2 (reference 2)– channel index 25
Mouse B3 (reference 2)– channel index 30
Mouse C1 (reference 1)– channel index 15
Mouse C2 (reference 1)– channel index 27
Mouse C3 (reference 1)– channel index 26
Mouse C4 (reference 1)– channel index 31

For guidance on how to read the data, please visit the following link https://github.com/tortlab/dentate-spikes.

Related pre-print

Santiago RMM, Lopes-dos-Santos V, Aery Jones, EA, Huang Y, Dupret D, Tort, ABL
Waveform-based classification of dentate spikes
2023. bioRxiv doi: 10.1101/2023.10.24.563826

References

1. Aery Jones EA, Rao A, Zilberter M, Djukic B, Bant JS, Gillespie AK, Koutsodendris N, Nelson M, Yoon SY, Huang K, Yuan H, Gill TM, Huang Y, Frank LM.
   Dentate gyrus and CA3 GABAergic interneurons bidirectionally modulate signatures of internal and external drive to CA1.
   2021. Cell Rep. 37(13):110159. doi: 10.1016/j.celrep.2021.110159
   • Associated dataset.

      

2. Lopes-dos-Santos V, Brizee D, Dupret D.
   Spatio-temporal organization of network activity patterns in the hippocampus.
   2023. bioRxiv doi: 10.1101/2023.10.17.562689.

    

3. Lopes-dos-Santos V, van de Ven GM, Morley A, Trouche S, Campo-Urriza N, Dupret D.
   Parsing Hippocampal Theta Oscillations by Nested Spectral Components during Spatial Exploration and Memory-Guided Behavior.
   2018. Neuron. 100(4):940-952.e7. doi: 10.1016/j.neuron.2018.09.031.

    

4. Senzai Y, Buzsáki G.
   Physiological Properties and Behavioral Correlates of Hippocampal Granule Cells and Mossy Cells.
   2017. Neuron. 93(3):691-704.e5. doi: 10.1016/j.neuron.2016.12.011.
   • Associated dataset (mouse subject from which waveforms were extracted).