Using Targeted Memory Reactivation to generate new, adaptive behaviours: code and data

Rawson AB, Nalluru S, O'Reilly JX, Barron HC
Description

Using a pre-registered task design and analysis, this dataset contains button press responses recorded during learning and test periods of a Targeted Memory Reactivation (TMR) task in humans. The task was designed to explore how contextual memory reactivation during awake rest influences consolidation of associative memory and the discovery of hidden relationships, such as non-directly trained relationships that support novel inference. The data have been used for the paper "Memory reactivation generates new, adaptive behaviours that reach beyond direct experience". 

The raw behavioural data from 40 participants is provided in MATLAB (.mat) format. It also includes MATLAB (.m) and Jupyter Notebooks (.ipynb) to analyse the data to generate all figures.

Please see the paper's Methods and Results sections for details of the experiment, and prerequisite versions of libraries and environments.

Assistance with this dataset

We welcome researchers wishing to reuse our data to contact the creators of datasets. If you are unfamiliar with analysing the type of data we are sharing, have questions about the acquisition methodology, need additional help understanding a file format, or are interested in collaborating with us, please get in touch via email. Our current members have email addresses on our main site. The corresponding author of an associated publication, or the first or last creator of the dataset are likely to be able to assist, but in case of uncertainty on who to contact, email Ben Micklem, Research Support Manager at the MRC BNDU.

An image of a person in three states: learning, rest and testing, the figures in 'learning' and 'rest' have headphones on, playing sounds. There are jumbled letters above the head of the 'learning' person, who is reading. The rest person is not reading, and above them there are links forming between nodes, the top row of nodes shows A B C, but not yet with links formed between them. In the final panel, 'Testing', which also shows a light being on, there person has a linked network of nodes, ABC being linked
Year Published
2024
DOI
10.60964/bndu-wv4h-0734
Funders
Medical Research Council (MR/W01971X/1, MR/L019639/1)
UKRI (MR/W008939/1)
Biotechnology and Biological Sciences Research Council (DDT00060_HM01.11)
Wellcome Trust (203139/Z/16/Z)
Clarendon Fund
Publisher
University of Oxford
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First Published In
Rawson AB, Nalluru S, O'Reilly JX, Barron HC
Memory reactivation generates new, adaptive behaviours that reach beyond direct experience.
2024. Sci Rep, 14(1):30097.
Free Full Text PDF here
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