Electrophysiological recordings of juxtacellularly labelled striatal interneurons in vivo

Sharott A
Doig N
Garas F
Vinciati F
Magill PJ
Description

Each MATLAB .mat file contains an electrophysiological recording of a single striatal interneuron and coincident electrocorticogram (ECoG). Neurons are only included in this data set if they were juxtacellularly labelled following recording, recovered post-mortem and confirmed to express either parvalbumin (PV), choline acetyl transferase (ChAT), nitric oxide synthase (NOS) or calretinin (CR).

All recordings were made from Sprague Dawley rats anaesthetised with urethane and supplemental doses of ketamine and xylazine. Detailed methods can be found in the references below.

Recordings were made in to brain states: slow wave activity (SWA) and cortical activation. Recordings are divided in to folders based on both their neurochemical identity and the state in which they were recorded.

Each folder contains neurons of a single neurochemical identity (chat, pv, nos or cr) recorded in one brain state (swa or Act).

Some neurons were recorded in both states. Names of neurons are consistent throughout so that neurons recorded in both states can be compared.

The electrophysiological data and their recording parameters are stored as structure arrays (“ephys”) with the following fields:

ephys.wideband

Data values of the wideband recording from the glass electrode (including both local field potential and action potential components).

ephys.highpass

Data values for the online highpass filtered 300 –5000 Hz wideband signal used to sort action potentials.

ephys.time_bin

Binary representation of the spike times of the sorted action potentials

ephys.ecog 

Data values for coincident ECoG recording

ephys.time_axis

Time axis for all electrophysiological recordings.

ephys.sr

Sampling rate of all electrophysiological recordings (all 16000)

ephys.amp_unit

Amplitude unit for all electrophysiological recordings (all mV)

striatal interneurons
Year Published
2019
DOI
10.5287/bodleian:VYqnPkxkb
Funders & Grant Numbers
Medical Research Council UK (U138197109)
Medical Research Council (MC_UU_12020/5)
Medical Research Council (MC_UU_12024/2)
Medical Research Council (MC_UU_12024/1
Medical Research Council UK (1531859)
Wellcome Trust (109030/Z/15/Z)
Wellcome Trust (101821)
Parkinson's UK (Grant number G-0806)
European Research Council (SNAP-PD)
Publisher
University of Oxford
First Published In
Sharott A, Doig NM, Mallet N, Magill PJ
2012. J. Neurosci., 32(38):13221-36.
Group
Sharott Group
Magill Group
Terms

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