fMRI, MRS, puppilometry and behavioural data acquired after noradrenaline manipulation during learning: data and code

Koolschijn RS, Browning M, Przygodda X, Capitão L, Clarke WT, O'Reilly JX, Barron HC
Description

In humans, we apply a double-blind pharmacological manipulation immediately before  participants learn a novel cognitive map (day 1). On the same day (day 1), functional Magnetic Resonance Imaging (fMRI), Magnetic Resonance Spectroscopy, behavioural and pupillometry data are acquired, while additional behavioural measures of memory are acquired on day 5.

The dataset consists of the following components:

  • Behavioural data from learning task, memory tests and scan task (mat)
  • raw MRS data (twix)
  • preprocessed MRS data in Gannet (.mat and Gannet output pdfs)
  • raw pupillometry data (edf)
  • preprocessed pupillometry data (mat)
  • fMRI group volumes (nifti)
  • fMRI extracted beta values (mat)
  • ROI used for analysis (nifti)

The code package contains MATLAB code for:

  • Generating the figures in Koolschijn et al., (2025)
  • The learning task and memory tests ran in Psychtoolbox. Please note that stimuli are not included due to copyright.
  • pupillometry data preprocessing (using the edf toolbox)
Assistance with this dataset

We welcome researchers wishing to reuse our data to contact the creators of datasets. If you are unfamiliar with analysing the type of data we are sharing, have questions about the acquisition methodology, need additional help understanding a file format, or are interested in collaborating with us, please get in touch via email. Our current members have email addresses on our main site. The corresponding author of an associated publication, or the first or last creator of the dataset are likely to be able to assist, but in case of uncertainty on who to contact, email Ben Micklem, Research Support Manager at the MRC BNDU.

Year Published
2025
DOI
10.60964/BNDU-Z7QY-JP81 
Metadata
DataCite XML
Funders
UKRI (MR/W008939/1)
Publisher
University of Oxford
Downloaded times
Group
Terms

Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0)

This is a human-readable summary of (and not a substitute for) the licence.

You are free to:

Share — copy and redistribute the material in any medium or format

Adapt — remix, transform, and build upon the material for any purpose, even commercially.

This licence is acceptable for Free Cultural Works. The licensor cannot revoke these freedoms as long as you follow the license terms. Under the following terms:

Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same licence as the original.

No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the licence permits.