STN local field potential recordings from awake patients with Parkinson’s, ON and OFF meds, and during 130 Hz DBS

Wiest C, Torrecillos F, Pogosyan A, Baig F, Pereira EA, Morgante F, Ashkan K, Tan H
Description

Subthalamic local field potential recordings from awake patients with Parkinson’s disease while leads were externalised. In 30 hemispheres, this data was recorded ON and OFF dopaminergic medication and in 26 hemispheres before and during 130 Hz deep brain stimulation of the subthalamic nucleus.

DBS data

This file contains subthalamic local field potential (LFP) data from 26 recordings.

MATRIX_DBS.metadata contains the hemisphere identifier (hemisphere_id, e.g. 'P5_L' denotes the left hemisphere of participant 5) and medication status (0 = OFF, 1 = ON) for each recording.

MATRIX_DBS.fs contains the corresponding sampling rates. MATRIX_DBS.signal_base contains resting LFP data without stimulation, and MATRIX_DBS.signal_dbs contains LFP data during 130 Hz deep brain stimulation of the subthalamic nucleus, as described in the corresponding article.

The ordering of recordings is consistent across metadata, fs, signal_base, and signal_dbs.

Medication data

This dataset was recorded for 30 hemispheres ON and OFF levodopa. Each file has more information on how the data is arranged: SmrData.WvTits. Channel titles denote EEGs (e.g. Fz, Cz, F3), bipolar LFP channels (e.g. Le02, R02, L13) or accelerometer data (e.g. AcX, AcY).

Assistance with this dataset

We welcome researchers wishing to reuse our data to contact the creators of datasets. If you are unfamiliar with analysing the type of data we are sharing, have questions about the acquisition methodology, need additional help understanding a file format, or are interested in collaborating with us, please get in touch via email. Our current members have email addresses on our main site. The corresponding author of an associated publication, or the first or last creator of the dataset are likely to be able to assist, but in case of uncertainty on who to contact, email Ben Micklem, Research Support Manager at the MRC BNDU.

diagram of the deep brain stimulation recording electrode with four contacts and the output to TMSi Porti/Saga
Year Published
2022
Copyright Years
2018-2022
DOI
10.5287/bodleian:mzJ7YwXvo
Metadata
DataCite XML
Funders
Medical Research Council, UKRI (MC_UU_00003/2, MC_UU_00003/5, MC_UU_00003/6, MR/V00655X/1, MR/P012272/1)
National Institute for Health Research Oxford Biomedical Research Centre
Rosetrees Trust
Parkinson's UK (G-0806)
Publisher
University of Oxford
Downloaded times
First Published In
Wiest C, Torrecillos F, Pogosyan A, Bange M, Muthuraman M, Groppa S, Hulse N, Hasegawa H, Ashkan K, Baig F, Morgante F, Pereira EA, Mallet N, Magill PJ, Brown P, Sharott A, Tan H
The aperiodic exponent of subthalamic field potentials reflects excitation/inhibition balance in Parkinsonism.
2023. eLife, 12:e82467
Free Full Text PDF here
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