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<response><xml version="1.0" encoding="UTF-8"><resource xmlns="http://datacite.org/schema/kernel-4" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://datacite.org/schema/kernel-4 http://schema.datacite.org/meta/kernel-4/metadata.xsd"><creators><creator><creatorName nameType="Personal">Gava GP</creatorName><givenName>Giuseppe P</givenName><familyName>Gava</familyName><nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org">https://orcid.org/0000-0002-0462-916X</nameIdentifier></creator><creator><creatorName nameType="Personal">McHugh SB</creatorName><givenName>Stephen B</givenName><familyName>McHugh</familyName><nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org">https://orcid.org/0000-0003-4739-453X</nameIdentifier></creator><creator><creatorName nameType="Personal">Lef&#xE8;vre L</creatorName><givenName>Laura</givenName><familyName>Lef&#xE8;vre</familyName><nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org">https://orcid.org/0009-0004-7713-1401</nameIdentifier></creator><creator><creatorName nameType="Personal">Lopes-Dos-Santos V</creatorName><givenName>V&#xED;tor</givenName><familyName>Lopes-Dos-Santos</familyName><nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org">https://orcid.org/0000-0002-1858-0125</nameIdentifier></creator><creator><creatorName nameType="Personal">Trouche S</creatorName><givenName>St&#xE9;phanie</givenName><familyName>Trouche</familyName></creator><creator><creatorName nameType="Personal">El-Gaby M</creatorName><givenName>Mohamady</givenName><familyName>El-Gaby</familyName><nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org">https://orcid.org/0000-0002-6344-3859</nameIdentifier></creator><creator><creatorName nameType="Personal">Schultz SR</creatorName><givenName>Simon R</givenName><familyName>Schultz</familyName><nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org">https://orcid.org/0000-0002-6794-5813</nameIdentifier></creator><creator><creatorName nameType="Personal">Dupret D</creatorName><givenName>David</givenName><familyName>Dupret</familyName><nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org">https://orcid.org/0000-0002-0040-1766</nameIdentifier></creator></creators><titles><title xml:lang="en">Topological analysis of hippocampal CA1 co-firing graphs</title></titles><resourceType resourceTypeGeneral="Dataset">Topological analysis of hippocampal CA1 co-firing graphs</resourceType><publisher>University of Oxford</publisher><publicationYear>2021</publicationYear><dates><date dateType="Issued">2021</date></dates><language>en</language><relatedIdentifiers><relatedIdentifier relatedIdentifierType="DOI" relationType="IsCitedBy">10.1038/s41593-021-00804-w</relatedIdentifier></relatedIdentifiers><rightsList><rights rightsURI="https://creativecommons.org/licenses/by-sa/4.0/legalcode">Creative Commons Attribution Share Alike 4.0 International</rights></rightsList><descriptions><description xml:lang="en" descriptionType="TechnicalInfo"><![CDATA[Each matrix contains the hippocampal CA1 co-firing graphs computed using the spike trains of pyramidal cells recorded from mice during active exploratory behaviour (i.e., excluding immobility epochs and sharp-wave/ripples) in four different tasks: (i) conditioned place preference (CPP), (ii) exploration of a novel context (without reward), (iii) spontaneous place preference (SPP) for a novel context and (iv) rewarded exploration of an otherwise familiar context (without CPP).

In these co firing graphs, each node represents one cell; the edge linking any two nodes represents the coactivity of that cell pair, with a weight computed as the Pearson correlation coefficient between their spike trains.

Each co-firing graph is defined by its adjacency matrix, whose elements are the edges of the graph / co-firing relationships between pairs of neurons indexed by the rows and columns of the matrix.

For each matrix, the code provided (python 3.6) analyses the co-firing relationships among pyramidal cells for the 6 sessions recorded on that task day. Graph-theoretical measures are obtained for each co-firing graph (one graph per task session) and their dynamics across the 6 task sessions are analysed. See the paper 'Integrating new memories into the hippocampal network activity space'&nbsp;for description of the task and detailed methods. Notably, these example co-firing graphs and codes relate to figures 1, 2 and extended data figure 2.
]]></description></descriptions><fundingReferences><fundingReference><funderName>Biotechnology and Biological Sciences Research Council, UKRI</funderName><awardNumber>BB/N002547/1</awardNumber></fundingReference><fundingReference><funderName>Medical Research Council, UKRI</funderName><awardNumber>MC_UU_12024/3</awardNumber></fundingReference><fundingReference><funderName>Medical Research Council, UKRI</funderName><awardNumber>MC_UU_00003/4</awardNumber></fundingReference></fundingReferences></resource></xml></response>
