STN LFPs from Parkinson’s patients during stepping in place

Fischer P
Brown P
Tan H
Description

These data contain local field potentials (LFPs) from the human subthalamic nucleus recorded from patients with Parkinson’s after receiving deep brain stimulation surgery.

Patients were asked to step on the spot (while sitting and for three data sets also while standing) and to synchronize their steps to the rhythm of a walking cartoon man displayed in a video.  The details of the experimental design and behavioural task are described in Fischer et al (2018). Results on decoding analyses, attempting to decode movement states within the gait cycle based on the STN LFPs, are reported in Tan et al (2018).

All LFPs were first recorded as monopolar signals with a common reference and the ground electrode attached to the wrist of the patient. Bipolar LFPs were constructed by computing the difference between monopolor recordings from neighbouring contacts. The timing of each heel strike was simultaneously recorded with foot pedals or force plates.

The compressed folder includes 16 files containing data from 13 participants in the study (+ 3 data sets recorded additionally during stepping while standing). The data files are in MATLAB format. Each file contains one data structure, the details of the structure is described in ‘Description.txt’ in the compressed folder.

A MATLAB script (plot_beta_power.m) to plot the beta power average for left and right STN activity aligned to the right heel strike is also provided.

Assistance with this dataset

We welcome researchers wishing to reuse our data to contact the creators of datasets. If you are unfamiliar with analysing the type of data we are sharing, have questions about the acquisition methodology, need additional help understanding a file format, or are interested in collaborating with us, please get in touch via email. Our current members have email addresses on our main site. The corresponding author of an associated publication, or the first or last creator of the dataset are likely to be able to assist, but in case of uncertainty on who to contact, email Ben Micklem, Research Support Manager at the MRC BNDU.

stepping figure
Year Published
2019
DOI
10.5287/bodleian:M81wpxae8
Funders & Grant Numbers
Medical Research Council (MR/P012272/1)
Medical Research Council (MC_UU_12024/1)
Parkinson Appeal UK
The Monument Trust
Publisher
University of Oxford
Downloaded times
First Published In
Fischer P, Chen CC, Chang YJ, Yeh CH, Pogosyan A, Herz DM, Cheeran B, Green AL, Aziz TZ, Hyam J, Little S, Foltynie T, Limousin P, Zrinzo L, Hasegawa H, Samuel M, Ashkan K, Brown P, Tan H
2018. J. Neurosci., 38(22):5111-5121.
Terms

Attribution-ShareAlike 4.0 International (CC BY-SA 4.0) This is a human-readable summary of (and not a substitute for) the licence. You are free to: Share — copy and redistribute the material in any medium or format Adapt — remix, transform, and build upon the material for any purpose, even commercially. This licence is acceptable for Free Cultural Works. The licensor cannot revoke these freedoms as long as you follow the license terms. Under the following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. ShareAlike — If you remix, transform, or build upon the material, you must distribute your contributions under the same licence as the original. No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the licence permits.